Related Experiment Video
Updated: May 10, 2025

03:45
Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
3.0K
Phenotypic Heterogeny of Hereditary Angioedema Within a Single Family
Josephine M Fails1, Selina A Gierer1
1The University of Kansas School of Medicine-Kansas City, Kansas City, Kansas.
Kansas Journal of Medicine
|April 25, 2025
Abstract
No abstract available in PubMed .
Related Concept Videos
Pedigree Analysis
82.1K
Overview
82.1K
Genetic Lingo
98.4K
Overview
98.4K
Multiple Allele Traits
33.8K
The Concept of Multiple Allelism
33.8K
Pleiotropy
37.9K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
37.9K
Genetic Variation
236
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
Genes exist in different versions called alleles,...
236
Law of Segregation
62.0K
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
62.0K

