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Closed Incision Negative Pressure Therapy Reduces Donor Site Complications in Head and Neck Reconstruction
Haruyuki Hirayama1, Katsuhiro Ishida1, Hiroki Kodama1
1Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, Tokyo, Japan.
The Laryngoscope
|April 25, 2025
Summary
Closed incision negative pressure therapy (ciNPT) significantly reduces complications in head and neck reconstruction flap harvest sites. This therapy improves surgical wound outcomes, decreasing risks like infection and dehiscence.
Area of Science:
- Plastic Surgery
- Surgical Oncology
- Wound Healing
Background:
- Head and neck reconstruction often involves complex flap harvest sites.
- Surgical wound complications can negatively impact patient outcomes.
- Closed incision negative pressure therapy (ciNPT) is a potential method to mitigate these complications.
Purpose of the Study:
- To evaluate the effectiveness of ciNPT in reducing complications at primarily closed flap harvest sites in head and neck reconstruction.
- To compare complication rates between patients who received ciNPT and those who did not.
Main Methods:
- Retrospective analysis of 85 head and neck reconstruction patients (2021-2024).
- Patients divided into ciNPT (n=46) and non-ciNPT (n=39) groups.
- Assessment of postoperative complications (dehiscence, necrosis, SSIs, hematomas, seromas) within 30 days.
- Multivariate logistic regression to identify risk factors.
Main Results:
- Overall complication rate was 15.3% (13/85 patients).
- ciNPT group had significantly lower complication rates (4.3%) compared to the non-ciNPT group (28.2%).
- Non-ciNPT use was associated with a 7.9-fold increased risk of complications (adjusted OR: 7.942; p=0.011).
- Complications in the ciNPT group were minor seromas; non-ciNPT group experienced more severe issues.
Conclusions:
- ciNPT is associated with a lower incidence of complications at flap harvest sites in head and neck reconstruction.
- The findings suggest ciNPT can improve postoperative wound outcomes.
- Further randomized controlled trials are recommended to validate these results.

