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Updated: May 10, 2025

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Striatal Toe: Too Harmless to Treat?

Wolfgang H Jost1,2, Emir Berberovic1

  • 1Parkinson-Klinik Ortenau, 77709 Wolfach, Germany.

Toxins
|April 25, 2025
PubMed
Summary
This summary is machine-generated.

Striatal toe, a hallux misalignment linked to Parkinsonism, impairs walking and quality of life. Botulinum neurotoxin (BoNT) shows promise for treatment, but further research is needed.

Keywords:
Parkinson’s diseasebotulinum neurotoxinstriatal toe

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Area of Science:

  • Neurology
  • Movement Disorders
  • Podiatry

Background:

  • Striatal toe is a dorsal flexion misalignment of the hallux.
  • It is a common symptom in Parkinson's disease and atypical Parkinsonian syndromes.
  • This condition significantly impacts daily activities, causes pain, and reduces quality of life.

Purpose of the Study:

  • To present contemporary data on the therapy of striatal toe using botulinum neurotoxin (BoNT).
  • To discuss the limited existing data on the prevalence, genesis, and therapy of striatal toe.
  • To identify and discuss open questions for future research in this area.

Main Methods:

  • Review and presentation of current clinical data on BoNT therapy for striatal toe.
  • Discussion of existing literature regarding striatal toe.
  • Identification of areas requiring further investigation and clinical trials.

Main Results:

  • Botulinum neurotoxin (BoNT) has demonstrated a positive effect in treating striatal toe.
  • Current study data on BoNT for striatal toe are limited.
  • Formal approval studies for BoNT in this indication have not yet been conducted.

Conclusions:

  • BoNT is a potential therapeutic option for striatal toe.
  • More comprehensive data and formal studies are required to establish efficacy and safety.
  • Further research should focus on prevalence, etiology, and standardized treatment protocols for striatal toe.