Association of psychosocial risk factors with acute outcomes of elective cancer resection in the United States
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Psychosocial risk factors independently predict worse outcomes in cancer surgery patients. Early identification and intervention are crucial for improving care and reducing adverse events.
Area Of Science
- Oncology
- Health Services Research
- Surgical Outcomes
Background
- Psychosocial risk factors (e.g., psychiatric disorders, substance use, low socioeconomic status) are recognized in cancer care.
- Their independent impact on acute postoperative outcomes after elective cancer surgery is not well-defined.
- This study investigates the association between psychosocial risk factors and clinical/financial outcomes in cancer surgery patients.
Purpose Of The Study
- To evaluate the independent association of psychosocial risk factors with mortality, complications, length of stay, and discharge disposition after elective cancer surgery.
- To identify specific clinical and financial outcomes affected by these risk factors.
Main Methods
- Utilized the 2016-2021 Nationwide Readmissions Database for adult patients undergoing elective cancer resections (lung, esophageal, gastric, pancreatic, hepatic, colon).
- Employed entropy balancing and multivariable regression models to analyze the independent effects of psychosocial risk factors.
- Assessed outcomes including mortality, complications (respiratory, infectious), length of stay, and non-home discharge.
Main Results
- Of ~655,376 patients, 34.2% had psychosocial risk factors, presenting with higher comorbidity.
- Psychosocial risk factors were independently associated with increased odds of mortality (aOR 1.43), respiratory complications (aOR 1.25), and infectious complications (aOR 1.17).
- Patients with psychosocial risk factors experienced incrementally increased resource utilization and longer hospital stays.
Conclusions
- Psychosocial risk factors are independent predictors of adverse clinical and financial outcomes following elective cancer surgery.
- Systematic screening for these factors can enable targeted interventions.
- Improving care for high-risk cancer patients necessitates addressing psychosocial determinants.
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
Related Concept Videos
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...