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Updated: Jul 25, 2026
04:30
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
25.4K
Long-Term Stent Patency and Revascularization Rates after Emergent Carotid Stenting during Stroke Thrombectomy.
Alexandru Dimancea1, Axelle Y Kern2, Francois Severac3
1From the Interventional Neuroradiology Department (A.D., A.H., I.L.-L.), Strasbourg University Hospitals, Strasbourg, France.
AJNR. American Journal of Neuroradiology
|April 25, 2025
Summary
Emergent carotid artery stenting for stroke shows most stent occlusions occur within 24 hours. Long-term restenosis rates are similar to elective procedures, but early occlusion needs further research.
Area of Science:
- Neuroendovascular therapy
- Cerebrovascular disease management
- Interventional neuroradiology
Background:
- Emergent carotid artery stenting (eCAS) during endovascular treatment (EVT) for acute ischemic stroke (AIS) is linked to higher stent thrombosis.
- Limited data exists on long-term carotid stent patency and target lesion revascularization (TLR) post-EVT.
Purpose of the Study:
- To evaluate long-term carotid stent patency and TLR rates after eCAS in patients with AIS.
- To identify the timing and incidence of stent occlusion and restenosis.
Main Methods:
- Retrospective analysis of a prospectively maintained stroke EVT database.
- Inclusion of 220 patients treated with eCAS for tandem lesions or isolated carotid artery occlusion between 2009-2024.
Main Results:
- Stent occlusion or severe stenosis occurred in 8.6% within 24 hours; only 1.3% occurred later.
- In-stent restenosis (≥50%) was observed in 4.3% at a median of 13 months, primarily in patients with carotid atheroma.
- Cumulative 1- and 2-year restenosis rates were 9.8% and 22%, respectively; TLR was performed in 3% of cases.
Conclusions:
- Stent occlusion predominantly occurs within the first 24 hours post-eCAS.
- Long-term in-stent restenosis rates are comparable to elective carotid artery stenting (CAS).
- Prospective research is needed to mitigate early stent occlusion rates.
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