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Updated: May 10, 2025

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
Strengthening arbovirus surveillance: bridging gaps for global health preparedness
Eleonora Cella1, Mónica V Cunha2, Luiz Carlos Junior Alcantara3
1Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Abstract:
Despite significant advancements in arbovirus research, contributions remain disproportionately focused on regions with reported major outbreaks of diseases such as dengue, Zika, and chikungunya. This bias risks neglecting potentially critical properties in viral evolution, transmission dynamics, ecological drivers, and host-pathogen interactions that occur within the less-studied areas. Recent developments highlight the importance of incorporating data from underrepresented regions and from recent surveillance approaches to uncover novel insights that could enhance global preparedness and response strategies. This opinion explores frameworks for generating and integrating diverse geographical data, proposing equitable research approaches to better capture the global heterogeneities and properties of at-risk environments and populations. A geographically inclusive perspective is essential to address emerging arboviral challenges, particularly in the context of a changing environment and shifting land use patterns.

