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Low-dose intravenous insulin therapy for diabetic ketoacidosis in children
American Journal of Diseases of Children (1960)
|March 1, 1977
Insights
Continuous low-dose intravenous insulin effectively and safely treated diabetic ketoacidosis in pediatric patients. This simple method achieved recovery with no observed complications in fourteen children.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
Background:
- Diabetic ketoacidosis (DKA) is a serious complication of diabetes.
- Effective and safe treatment protocols for pediatric DKA are crucial.
Purpose of the Study:
- To evaluate the efficacy and safety of continuous low-dose intravenous insulin for treating pediatric DKA.
- To assess the required insulin dosage and potential complications.
Main Methods:
- Fourteen pediatric patients diagnosed with DKA were treated.
- A continuous low-dose intravenous insulin regimen was administered.
- Dosage was 0.25 units/kg every four hours, totaling an average of 0.6 units/kg for recovery.
Main Results:
- All fourteen pediatric patients achieved successful recovery from DKA.
- Average admission blood glucose was 717 mg/100 ml and mean blood pH was 7.13.
- No treatment-related complications were observed during the study.
Conclusions:
- Continuous low-dose intravenous insulin is an effective and safe treatment for pediatric DKA.
- The method is simple to administer, making it a viable option for clinical practice.
Abstract:
Fourteen pediatric patients were successfully treated for diabetic ketoacidosis with continuous low-dose intravenous insulin. The average admission blood glucose concentration was 717 mg/100 ml and the mean admission capillary blood pH was 7.13. The insulin dosage was 0.25 units/kg every four hours. The average total insulin dose for recovery was 0.6 units/kg. No complication was observed. The method is effective, safe, and simple to administer.