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Disability is a risk factor for 1-year mortality after TB diagnosis
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Summary
People with tuberculosis (TB) and disabilities face a higher risk of death within one year of diagnosis. This study highlights the urgent need for targeted healthcare strategies to improve survival rates for this vulnerable population.
Area of Science:
- Public Health
- Epidemiology
- Disability Studies
Background:
- Individuals with disabilities are disproportionately affected by tuberculosis (TB).
- Understanding the impact of disability on TB outcomes is crucial for public health interventions.
Purpose of the Study:
- To investigate the association between disability and 1-year mortality in patients diagnosed with TB.
- To quantify the excess mortality risk faced by people with disabilities after TB diagnosis.
Main Methods:
- A nationwide, population-based cohort study was conducted in the Republic of Korea.
- Linked national registry data from 2008-2016 included 317,597 active TB cases.
- Cox proportional hazard models analyzed 1-year mortality risk in relation to disability status.
Main Results:
- People with disabilities had a significantly higher incidence of all-cause mortality (7.77 vs. 2.85 per 1,000 person-months).
- Disability was strongly associated with increased 1-year mortality (aHR 1.24).
- Severe disabilities further elevated mortality risk (aHR 1.60), with increased TB-related and non-TB-related deaths.
Conclusions:
- People with disabilities experience a substantially higher 1-year mortality rate following TB diagnosis.
- These findings emphasize the critical need for tailored healthcare interventions and support systems for TB patients with disabilities.
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