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Factors Associated with Combination Therapy Involving Traditional Korean Medicine in Pediatric Allergic Rhinitis

Mi Ju Son1, Kyung-Min Shin1, Changsop Yang1

  • 1KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.

Healthcare (Basel, Switzerland)
|April 26, 2025
PubMed

Insights

This study found that school-aged children, winter season, and comorbidities like atopic dermatitis predict combination therapy use in pediatric allergic rhinitis (AR) patients. Integrating traditional Korean medicine (KM) may benefit these children.

Area of Science:

  • Pediatric Allergy and Immunology
  • Integrative Medicine
  • Health Services Research

Background:

  • Allergic rhinitis (AR) significantly impacts children's quality of life and healthcare systems.
  • Prevalence of pediatric AR is increasing globally.
  • Combination therapy with traditional Korean medicine (KM) and conventional medicine is utilized for pediatric AR.

Purpose of the Study:

  • To investigate factors associated with KM combination therapy use in pediatric AR patients.
  • To analyze large-scale health insurance data for insights into treatment patterns.
  • To identify predictors of combined therapy utilization.

Main Methods:

  • Analysis of health insurance data from 696,182 pediatric AR patients (2018-2021).
  • Multivariate logistic regression to identify factors influencing KM therapy utilization.
  • Comparison of treatment duration and healthcare costs between therapy groups.

Main Results:

  • 61,745 pediatric AR patients received KM combination therapy.
  • Predictors of KM combination therapy included school-age, winter season, and comorbidities (e.g., atopic dermatitis).
  • KM combination therapy was associated with longer treatment durations and higher costs; COVID-19 pandemic saw a decline in KM use.

Conclusions:

  • Integrating KM into pediatric AR treatment may offer benefits, particularly for children with comorbidities or during winter.
  • Findings can inform targeted healthcare policies for optimizing pediatric AR management.
  • Further research into the efficacy and cost-effectiveness of KM combination therapy is warranted.

Keywords:
National Health Insurance dataallergic rhinitispediatricstraditional Korean medicine

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