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Inflammatory Myofibroblastic Tumor: An Updated Review
1Department of Pathology, Yeungnam University College of Medicine, Daegu 42415, Republic of Korea.
Cancers
|April 26, 2025
Summary
Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with diverse presentations. This review updates on IMT
Area of Science:
- Oncology
- Pathology
Background:
- Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm.
- IMT is characterized by myofibroblastic/fibroblastic spindle cells and inflammatory infiltrate.
- Common sites include abdomen, retroperitoneum, and lung, especially in young individuals.
Purpose of the Study:
- To provide comprehensive updates on Inflammatory myofibroblastic tumor (IMT).
- To highlight clinical, molecular, and pathological characteristics.
- To review diagnostic approaches and differential diagnoses.
Main Methods:
- Literature review of clinical, pathological, and molecular data on IMT.
- Analysis of diagnostic challenges and differential diagnoses.
- Synthesis of recent advancements in IMT understanding.
Main Results:
- IMT exhibits local invasion/recurrence, with rare metastasis.
- Diagnostic challenges arise from overlapping features with other lesions.
- Histological heterogeneity and molecular diversity complicate management.
Conclusions:
- Accurate diagnosis of IMT is crucial for management and prognosis.
- Despite advancements, IMT remains challenging due to its complexity.
- This review synthesizes current knowledge on IMT characteristics and diagnosis.
Keywords:
epithelioid inflammatory myofibroblastic sarcomainflammatory myofibroblastic tumorinflammatory pseudotumormolecular geneticstumor classificationMore Related Videos
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