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An Ignored Population in Emergency Department: Cardio-Oncology Patients

Ömer Salt1, Cafer Zorkun2, Semra Aytürk Salt3

  • 1Department of Emergency Medicine, Kayseri City Training and Research Hospital, Kayseri 38060, Turkey.

Life (Basel, Switzerland)
|April 26, 2025
PubMed

Insights

Cancer patients with cardiac symptoms face high risks. Elevated NTproBNP, low LVEF, and high HEART/TIMI scores indicate increased cardiac toxicity and mortality risk.

Area of Science:

  • Cardiology
  • Oncology
  • Emergency Medicine

Background:

  • Cancer patients frequently present with cardiac symptoms.
  • Understanding cardiac events in cancer patients is crucial for effective management.

Purpose of the Study:

  • To analyze cancer patients admitted to the emergency department with cardiac symptoms.
  • To identify risk factors for cardiac toxicity and mortality in this population.

Main Methods:

  • Retrospective analysis of 131 cancer patients hospitalized over 5 years.
  • Evaluation of demographics, cancer type, treatment, diagnoses, lab parameters, and outcomes.
  • Focus on emergency department presentations and cardiology admissions.

Main Results:

  • Acute coronary syndromes were the most common diagnosis (69.5%).
  • Overall in-hospital mortality was 14.5%.
  • Elevated NTproBNP levels were observed, particularly in patients with left ventricular ejection fraction (LVEF) < 40%.

Conclusions:

  • Low LVEF, elevated NTproBNP, and high HEART/TIMI scores predict increased cardiac toxicity and mortality risk.
  • This high-risk group requires careful treatment and monitoring.
  • Early identification and intervention are key for improving outcomes in cancer patients with cardiac symptoms.

Keywords:
cardiologyemergencyoncology

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