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Updated: May 5, 2026

Isolation of Valvular Endothelial Cells
Published on: December 29, 2010
Infective or Non-Infective Endocarditis: A Brief Literature Review Based on a Case Report
Vasiliki Tsolaki1, George E Zakynthinos2, Konstantina Deskata1
1Critical Care Department, University Hospital of Larissa, Faculty of Medicine, University of Thessaly, Mezourlo, 41335 Larissa, Greece.
A patient with multiple myeloma developed severe influenza-induced acute respiratory distress syndrome (ARDS), leading to multiple cardiac valve lesions. This case highlights potential cardiac complications in immunocompromised patients with ARDS.
Area of Science:
- Cardiology
- Infectious Diseases
- Hematology
Background:
- The patient had a history of multiple myeloma undergoing treatment.
- Presented to the intensive care unit with fever and respiratory failure.
- Required intubation due to acute respiratory distress syndrome (ARDS) secondary to influenza.
Purpose of the Study:
- To describe a unique case of cardiac valve lesions in a patient with multiple myeloma and influenza-induced ARDS.
- To review the current literature on cardiac complications in similar clinical scenarios.
Main Methods:
- Case report presentation with a step-by-step approach.
- Clinical questions integrated into the case narrative.
- Comprehensive literature review on cardiac valve lesions in immunocompromised patients with ARDS.
Main Results:
- Cardiac ultrasonography revealed multiple lesions on the aortic, mitral, and tricuspid valves.
- The patient's presentation included fever, respiratory failure, and ARDS.
- The findings suggest a potential link between the patient's condition and the observed cardiac pathology.
Conclusions:
- Influenza-induced ARDS can lead to significant cardiac valve lesions, particularly in immunocompromised individuals.
- This case underscores the importance of cardiac monitoring in patients with multiple myeloma experiencing severe infections.
- Further research is warranted to elucidate the mechanisms and clinical implications of these cardiac findings.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Myocarditis I: Introduction
Pericarditis I: Introduction

