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Updated: May 10, 2025
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The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
180
The Intersection of Sarcopenia and Musculoskeletal Pain: Addressing Interconnected Challenges in Aging Care
Yacov Grosman1,2, Leonid Kalichman1
1Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel.
Summary
Sarcopenia and musculoskeletal pain worsen each other in older adults through shared factors like inactivity and inflammation. Integrated care and exercise are key to managing these interconnected conditions for better aging.
Area of Science:
- Gerontology
- Musculoskeletal Health
- Aging Research
Background:
- Global aging population experiences rising sarcopenia and musculoskeletal (MSK) pain.
- These conditions negatively impact physical function, quality of life, and independence in older adults.
- Emerging evidence suggests a bidirectional relationship where sarcopenia and MSK pain exacerbate each other.
Purpose of the Study:
- To explore the bidirectional relationship between sarcopenia and MSK pain.
- To highlight shared underlying mechanisms contributing to their mutual progression.
- To advocate for integrated, multidisciplinary care strategies for older adults.
Main Methods:
- Perspective review of current evidence on sarcopenia and MSK pain.
- Identification of shared etiological factors (inactivity, inflammation, hormonal changes, psychosocial factors).
- Discussion of integrated care models, screening, exercise, and nutrition.
Main Results:
- Sarcopenia and MSK pain share common pathways including inactivity, cellular aging, chronic inflammation, hormonal shifts, and psychosocial issues.
- These shared factors create a cycle of mutual exacerbation between the two conditions.
- Multidisciplinary and hybrid care models show promise for managing these interconnected conditions.
Conclusions:
- Addressing sarcopenia and MSK pain requires a holistic, integrated approach.
- Comprehensive screening, tailored exercise, nutritional support, and innovative care delivery are essential.
- Collaboration among clinicians, policymakers, and researchers is crucial to improve care for aging adults.
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