Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ochronotic cardiovascular disease.

M Ptacin, J Sebastian, V S Bamrah

    Clinical Cardiology
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Ochronosis, a tyrosine metabolism disorder, can affect the heart. This case highlights the cardiovascular complications associated with ochronosis, offering insights into disease progression.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anaesthesia for resection of vestibular schwannoma.

    BJA education·2025
    Same author

    Detection of other pathologies when utilising computer-assisted digital solutions for TB screening.

    IJTLD open·2024
    Same author

    Dexmedetomidine target controlled infusion for awake craniotomy<sup>†</sup>.

    Anaesthesia reports·2024
    Same author

    Dexmedetomidine as a rescue agent during intracranial neurosurgery in the setting of opioid tolerance.

    Anaesthesia reports·2022
    Same author

    Reducing occupational exposure to volatile anaesthetics - a reply.

    Anaesthesia·2018
    Same author

    Evaluation of a novel waste anaesthetic gas scavenger device for use during recovery from anaesthesia.

    Anaesthesia·2017
    Same journal

    Comparing Ferric Carboxymaltose Versus Iron Sucrose in Patients with Heart Failure.

    Clinical cardiology·2026
    Same journal

    Beyond Rural Versus Urban: Referral Pathways and Structural Heart Programs May Influence Outcomes After Left Atrial Appendage Occlusion.

    Clinical cardiology·2026
    Same journal

    Strauss-Defined LBBB Identifies Patients With Improved Outcomes After CRT-D: A Comparative Cohort Study.

    Clinical cardiology·2026
    Same journal

    Does Serum γKlotho Truly Provide Incremental Prognostic Value Beyond Established Risk Predictors in Multivessel Coronary Artery Disease?

    Clinical cardiology·2026
    Same journal

    Associations of the C-Reactive Protein-Albumin-Lymphocyte Index, Red Cell Distribution Width-Albumin Ratio, and Blood Urea Nitrogen-Albumin Ratio With All-Cause and Cardiovascular Mortality Among Adults With Preclinical Heart Failure.

    Clinical cardiology·2026
    Same journal

    Real-World National Databases Versus Hypothesis-Driven Cohort Studies: A Reply to the Critique on the TURK-HF Registry Design.

    Clinical cardiology·2026
    See all related articles

    Area of Science:

    • Biochemistry
    • Metabolic Disorders
    • Cardiovascular Medicine

    Background:

    • Ochronosis is a rare metabolic disorder characterized by the abnormal accumulation of homogentisic acid, a tyrosine metabolite.
    • While typically linked to alcaptonuria and spondyloarthropathy, cardiovascular manifestations are increasingly recognized.
    • Understanding these associations is crucial for comprehensive patient management.

    Observation:

    • This report details a specific case of ochronosis.
    • The case serves to exemplify the spectrum of cardiovascular abnormalities observed in patients with this condition.
    • Detailed clinical and pathological findings related to cardiovascular involvement are presented.

    Findings:

    • The case demonstrates significant cardiovascular findings associated with ochronosis.

    Related Experiment Videos

  • Specific abnormalities, such as valvular disease and myocardial changes, are highlighted.
  • The findings underscore the systemic impact of this metabolic disease.

    • Implications:

    • The cardiovascular complications of ochronosis require careful monitoring and proactive management.
    • Early recognition of cardiac involvement can lead to improved patient outcomes.
    • Further research into the mechanisms underlying cardiovascular damage in ochronosis is warranted.