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Published on: January 24, 2018
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Tarsal Tunnel Syndrome Following a Total Knee Replacement
Michael S Nirenberg1, Roberto P Segura2
1*Friendly Foot Care, PC, Crowne Point, IN.
Journal of the American Podiatric Medical Association
|April 26, 2025
Summary
Tarsal tunnel syndrome (TTS) can occur after knee replacement surgery. This case study details a patient who successfully recovered after nerve decompression surgery for TTS following a total knee replacement.
Area of Science:
- Orthopedics
- Neurology
- Podiatry
Background:
- Tarsal tunnel syndrome (TTS) involves tibial nerve compression in the ankle.
- The incidence of TTS post-total knee replacement (TKR) is not well-documented.
- This study presents a unique case of TTS developing after TKR.
Purpose of the Study:
- To report a rare case of TTS following TKR.
- To highlight potential extrinsic causes of TTS.
- To emphasize the importance of comprehensive patient history in diagnosing TTS.
Main Methods:
- Case report of a 78-year-old female patient.
- Clinical evaluation including history, physical examination, and imaging.
- Electrodiagnostic (EDX) studies to confirm nerve compression.
- Surgical intervention (nerve decompression) after conservative treatment failure.
Main Results:
- The patient developed left-sided TTS two weeks post-TKR.
- EDX studies confirmed tibial nerve entrapment.
- Post-operative pain significantly decreased from 5/10 (walking) and 10/10 (night) to 0/10.
- All TTS symptoms resolved after surgery.
Conclusions:
- TKR can be an unusual extrinsic cause of TTS.
- A detailed patient history is crucial for diagnosing TTS.
- Nerve decompression surgery can effectively treat TTS in this context.

