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Updated: Jul 15, 2026

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
NRDN: A novel nuclear degradation tag for targeted protein regulation in Arabidopsis
Liting Shen1, Huizhen Huang1, Daqi Yan2
1Synthetic Biology Center, Haixia Institute of Science and Technology, School of Future Technology, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Abstract:
The regulation of protein levels in plants is essential for improving agricultural productivity. Recent studies have explored inducible degradation systems in plants, with some showing promising advancements. This study introduces the NRDN degradation tag as a novel tool for regulating protein stability within the nucleus in Arabidopsis thaliana. Unlike traditional gene knockout methods, NRDN offers real-time, dynamic control over protein degradation, enabling precise studies of nuclear-localized proteins. This discovery provides a valuable tool for regulating protein stability in specific cellular compartments, which presents a versatile approach for dissecting complex cellular processes and offers broad applications in functional genomics and cellular research.
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