Related Experiment Video
Updated: May 10, 2025

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Peritoneal dialysis in congestive heart failure: reflections from a patient with arrhythmogenic right ventricular
Wilbert M T Janssen1, Jacobus C Karper2, Amarens van der Vaart3
1Department of Internal Medicine, Martini Hospital, Groningen, Groningen, The Netherlands w.m.t.janssen@mzh.nl.
Abstract:
After multiple hospitalisations for diuretic-resistant acute decompensated heart failure (ADHF), an early 60s man with isolated right-sided heart failure due to arrhythmogenic right ventricular cardiomyopathy (ARVC) underwent continuous venovenous haemofiltration without lasting success. His blood urea nitrogen/creatinine ratio was high and renal blood flow and filtration fraction were low, indicative of the underlying cardiorenal dysbalance. Peritoneal dialysis (PD) was initiated because this form of renal replacement therapy provides better haemodynamic stability and a flexible schedule. This allowed the patient to maintain his professional activities and spend time with his family for the subsequent 7 months. Following a diabetic foot infection, his condition worsened, leading to his death. Autopsy showed fibrofatty replacement of the right ventricle and chronic ischaemic nephropathy, without signs of hypertensive or diabetic nephropathy.Although ARVC is rare, this case underscores the potential benefits of PD as a palliative option in end-stage heart failure. Early consideration of PD, particularly when other renal replacement therapies are limited or contraindicated, may alleviate symptoms and enhance quality of life, especially after repeated hospitalisations for heart failure and kidney injury. Collaborative care between cardiologists and nephrologists is essential for optimising management in these patients.
Related Concept Videos
Heart Failure Drugs: Diuretics
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to...
Pathophysiology of Heart Failure
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...

