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Multiscale deformed attention networks for white blood cell detection
Xin Zheng1,2, Qiqi Xu3, Shiyi Zheng3
1School of Computer and Information, Anqing Normal University, Anqing, 246133, China. zxaoyou@aqnu.edu.cn.
Scientific Reports
|April 26, 2025
Summary
This study introduces MCDAF-Net, a novel deep learning model for accurate white blood cell (WBC) detection. The new method combines CNNs and Transformers to improve diagnostic capabilities for infections and cancers.
Area of Science:
- Medical Diagnostics
- Computer Vision
- Artificial Intelligence
Background:
- White blood cell (WBC) detection is critical for diagnosing various medical conditions.
- Traditional WBC detection methods are inefficient and time-consuming.
- Existing deep learning models like CNNs face challenges with global information and long-distance dependencies in WBC images.
Purpose of the Study:
- To develop an advanced deep learning model for accurate and efficient WBC detection.
- To overcome the limitations of current methods in handling large foreground-background differences in WBC images.
Main Methods:
- Introduction of the Multi-Scale Cross-Deformation Attention Fusion Network (MCDAF-Net), integrating Convolutional Neural Networks (CNNs) and Transformers.
- Development of the Attention Multi-scale Sensing Module (AMSM) for enhanced feature representation and accurate localization.
- Implementation of the Cross-Deformation Convolution Module (CDCM) to reduce feature correlation and improve generalization.
Main Results:
- MCDAF-Net demonstrates superior performance compared to existing models on public datasets (LISC, BCCD, WBCDD).
- The model effectively addresses challenges related to global information and long-distance dependencies in WBC image analysis.
- The fusion of CNNs and Transformers, along with specialized modules, leads to improved WBC detection accuracy.
Conclusions:
- MCDAF-Net offers a significant advancement in automated WBC detection.
- The proposed method holds promise for improving the speed and accuracy of medical diagnostics.
- The study provides a novel approach combining multi-scale feature fusion and attention mechanisms for cell detection.

