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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Reversible dilated cardiomyopathy in systemic lupus erythematosus: A case report
Jorge Reis1, Marta Leite2, Guilherme Jesus1
1Internal Medicine Department, Unidade Local de Saúde Gaia/Espinho, Vila Nova de Gaia, Portugal.
Lupus
|April 28, 2025
Summary
Systemic lupus erythematosus (SLE) can cause new-onset heart failure with reduced ejection fraction (HFrEF). Early diagnosis and treatment of SLE are crucial for improving cardiac function in patients with heart failure and systemic symptoms.
Area of Science:
- Cardiology
- Rheumatology
- Immunology
Background:
- Heart failure with reduced ejection fraction (HFrEF) is a serious condition.
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
- Cardiac manifestations of SLE, such as dilated cardiomyopathy, are rare but severe.
Purpose of the Study:
- To report a case of new-onset HFrEF secondary to SLE.
- To highlight the importance of recognizing SLE in patients presenting with de novo heart failure and systemic symptoms.
- To emphasize the potential for cardiac function improvement with early diagnosis and management of autoimmune diseases.
Main Methods:
- Case presentation of a 40-year-old woman.
- Clinical evaluation including assessment of systemic symptoms (arthralgia, cutaneous lesions, Raynaud's phenomenon).
- Diagnostic workup for heart failure and autoimmune disease, leading to diagnosis of SLE and dilated cardiomyopathy.
Main Results:
- The patient presented with de novo HFrEF and systemic symptoms.
- Diagnosis of SLE was established, with dilated cardiomyopathy identified as a secondary manifestation.
- Early management of SLE led to substantial improvement in cardiac function.
Conclusions:
- Dilated cardiomyopathy can be a rare, severe manifestation of SLE.
- Comprehensive evaluation is essential for patients with de novo heart failure and systemic symptoms.
- Timely diagnosis and treatment of underlying autoimmune conditions can significantly improve cardiac outcomes.
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