On the Knowledge and Prescription of Probiotics by Pediatric Providers: A Cross-Sectional Study

Uzma Rani1,2, Julie Ehrlich1,3, Ghina Fakhri1

  • 1State University of New York Upstate Medical University, Syracuse, NY 13210, USA.

Nutrients
|April 28, 2025
PubMed

Insights

Pediatric providers show gaps in understanding probiotics, with about half misdefining them. Despite this, most clinicians are asked about probiotics and many prescribe them, particularly for antibiotic-associated diarrhea.

Area of Science:

  • Pediatric Medicine
  • Microbiome Research
  • Gastroenterology

Background:

  • The efficacy and safety of probiotics for therapeutic or prophylactic use remain incompletely understood.
  • There is a need to evaluate the current knowledge and clinical application of probiotics among healthcare professionals caring for children.

Purpose of the Study:

  • To assess the knowledge and practice patterns regarding probiotic use in pediatric patients among pediatric providers.
  • To identify potential gaps in understanding and application of probiotic therapy in pediatric care.

Main Methods:

  • A cross-sectional survey was administered to members of the American Academy of Pediatrics, New York Chapter 1.
  • Data were collected from 168 responding pediatric providers regarding their knowledge and prescribing habits of probiotics.

Main Results:

  • Approximately 50% of respondents could not correctly define probiotics, confusing them with prebiotics and synbiotics.
  • Nearly all practitioners (97%) were queried by families about probiotics, and 60% had prescribed them, most commonly for antibiotic-associated diarrhea.
  • While a significant association between practice type and probiotic prescription existed, it diminished after adjustments; increased practitioner experience correlated with lower odds of prescription.

Conclusions:

  • General pediatric providers demonstrate insufficient knowledge regarding probiotics.
  • Despite knowledge deficits, most providers recommended continuing probiotics if families were already using them for a specific condition.
  • Further research with larger, nationally representative samples is warranted to better understand probiotic use in pediatrics.
Abstract