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Nano Selenium: A Promising Solution for Infectious Diseases - Current Status and Future Prospects.
Shaheen Husain1, Rania Mohammad Sabri Sultan2, Kirti Saxena3
1Amity Institute of Pharmacy, Amity University Uttar Pradesh (AUUP), Sec. 125, Noida, 201313, India.
Current Pharmaceutical Design
|April 28, 2025
Summary
Selenium nanoparticles (SeNPs) show promise in combating antibiotic resistance due to their antibacterial and antiviral properties. These nanoparticles offer a novel therapeutic approach for infectious diseases, with potential applications in medicine.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Rising antibiotic resistance necessitates novel antibacterial drug discovery.
- Nanoparticles are being investigated for their antibacterial and antiviral medicinal potential.
- Previous research highlights the role of nanoparticles in treating microbial diseases.
Purpose of the Study:
- To investigate the role of Selenium nanoparticles (SeNPs) against infectious diseases.
- To explore the probable mechanisms of action for SeNPs in treating infections.
Main Methods:
- Exploiting nanoparticles as delivery mechanisms and broad-spectrum inhibitors.
- Utilizing the high surface area to volume ratio of nanoparticles for diverse therapeutic applications.
- Synthesizing nanoparticles, with a focus on Selenium nanoparticles (SeNPs) for their biological relevance and environmental friendliness.
Main Results:
- Selenium nanoparticles (SeNPs) demonstrate significant therapeutic potential against infectious diseases.
- SeNPs show promise as effective delivery agents and potent antimicrobial materials.
- These findings position SeNPs as valuable in addressing antibiotic resistance.
Conclusions:
- Selenium nanoparticles (SeNPs) exhibit favorable biocompatibility, bioavailability, and low toxicity, making them promising biological agents.
- SeNPs possess chemopreventive, anti-inflammatory, and antioxidant properties, with potential applications in treating infections, cancer, and diabetes.
- Functionalized SeNPs offer enhanced therapeutic benefits, including improved absorption, bioavailability, and antimicrobial action compared to larger particles.
