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Updated: May 10, 2025

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
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Optical coherence tomography in soft matter.

Kasra Amini1, Cornelius Wittig1, Sofia Saoncella1

  • 1FLOW, Dept. of Engineering Mechanics, KTH, Stockholm SE-100 44, Sweden. kasraa@kth.se.

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Summary
This summary is machine-generated.

Optical coherence tomography (OCT) is a powerful, non-invasive tool for studying soft matter and fluid mechanics. This guide offers practical tutorials and case studies for researchers using OCT for complex dynamic systems.

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Area of Science:

  • Physics
  • Engineering
  • Materials Science

Background:

  • Optical coherence tomography (OCT) provides high-resolution, non-invasive measurements.
  • It bridges experimental gaps in studying mesoscopic features in soft matter and fluid mechanics.
  • OCT enables investigation of complex, confined, and dynamic systems.

Purpose of the Study:

  • To introduce Optical coherence tomography (OCT) to researchers.
  • To provide a practical guide for adopting OCT technology.
  • To illustrate OCT's versatility through case studies and tutorials.

Main Methods:

  • Review of intensity- and Doppler-based OCT techniques.
  • Provision of tutorials and Python scripts for OCT implementation.
  • Demonstration of OCT applications in fluid mechanics and soft matter.

Main Results:

  • OCT facilitates time-resolved velocimetry and particle-based velocity measurements.
  • It enables slip velocity characterization and detection of shear-induced structures.
  • OCT is effective for analyzing fluid-fluid and fluid-structure interactions.

Conclusions:

  • OCT is an indispensable tool for mesoscopic investigations in soft matter and fluid mechanics.
  • Practical guidelines and tutorials are provided to aid researchers in adopting OCT.
  • The review highlights OCT's broad applicability in studying dynamic and complex systems.