Single dose therapy with temocillin in acute gonorrhoea

Temocillin has pronounced in vitro activity against both penicillin-sensitive and penicillinase-producing gonococci. A single intramuscular injection of temocillin 0.5 g or 1.0 g resulted in the disappearance of the infecting gonococci in 91% of 75 patients and 94% of 192 patients in 2 separate trials. The systemic and local tolerance of the drug was unusually favourable and no serious side effects were observed.