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Updated: May 10, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Cutaneous Metastasis Mimicking a Pyogenic Granuloma Revealing Renal Cell Carcinoma
Meryem Soughi1,2, Riham Alheyasat3, Hanane Baybay1,2
1Department of Dermatology, University Hospital Hassan II, Unités de Recherche Labellisées (URL) Centre National pour la Recherche Scientifique et Technique (CNRST) N15, Fez, MAR.
Abstract:
Renal cell carcinoma (RCC) is a malignancy that can, in rare cases, present initially with cutaneous metastases, often reflecting an advanced stage. We report the case of a 71-year-old asymptomatic patient who presented with a gradually enlarging, raised lesion on the face over two years, clinically resembling a pyogenic granuloma. An excisional biopsy confirmed the diagnosis of cutaneous metastasis from clear cell RCC. Further staging investigations revealed a mass in the upper pole of the left renal cortex, a suspicious lesion in the lower pole, and bilateral pulmonary nodules, suggesting metastatic spread. The patient was started on sunitinib, resulting in both clinical and radiological improvement.
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