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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
45
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
22
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Related Experiment Video

Updated: May 10, 2025

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
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Visualizing global progress and challenges in esophagogastric variceal bleeding.

De-Xin Wang1,2,3,4, Xue-Jie Wu5, Jin-Zhong Yu6

  • 1Cell Biology Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

World Journal of Gastrointestinal Surgery
|April 28, 2025
PubMed
Summary

This bibliometric analysis reveals a significant increase in research on esophagogastric variceal bleeding (EGVB) over 20 years. Key focus areas include risk assessment and diagnostic optimization for improved patient outcomes.

Keywords:
BibliometricsEsophagogastric variceal bleedingLiver cirrhosisNon-cirrhotic portal hypertensionPortal hypertensionVisualization

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Area of Science:

  • Bibliometric analysis of medical research trends.
  • Gastroenterology and Hepatology.
  • Clinical research methodology.

Background:

  • Esophageal and gastric variceal bleeding (EGVB) is a severe complication of portal hypertension, often linked to liver cirrhosis.
  • Existing research is fragmented due to disease complexity and lack of standardized treatments.
  • Bibliometric analysis offers a systematic approach to understand research landscapes and identify future directions.

Purpose of the Study:

  • To evaluate research trends and advancements in esophagogastric variceal bleeding (EGVB) over the past two decades.
  • To identify core research topics, leading contributors, and emerging areas in EGVB research.
  • To provide insights for future clinical practice and scientific investigation in EGVB.

Main Methods:

  • Bibliometric analysis of publications on EGVB from the Web of Science Core Collection (2004-2023).
  • Utilized VOSviewer, Pajek, and CiteSpace for visualization of publication data.
  • Analyzed publication volume, geographical distribution, institutional contributions, key journals, authors, and keywords.

Main Results:

  • A total of 2097 EGVB-related publications were identified, showing a significant increase from 2004 to 2023.
  • China and the United States are leading countries in EGVB research; key institutions and journals were identified.
  • Core keywords highlight the importance of portal hypertension, management, liver cirrhosis, risk, prevention, and diagnosis in EGVB research.

Conclusions:

  • Bibliometric analysis demonstrates a clear research trajectory in EGVB, with current emphasis on risk assessment and diagnostic optimization.
  • Future research should prioritize multidisciplinary collaboration, personalized treatment strategies, and the development of novel diagnostic tools.
  • This study provides a systematic perspective and practical directions for advancing EGVB research and clinical management.