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Deep Brain Stimulation for Post-Hypoxic Myoclonus: A Case Correlating Local Field Potentials to Clinical Outcome
Harleen Kaur1, Tim J Goble2, Albert Fenoy3
1Department of Neurology, Louisiana State University Health Shreveport, Shreveport, LA, USA.
Background:
Post-hypoxic myoclonus (PHM) is characterized by generalized myoclonus after hypoxic brain injury. PHM is often functionally impairing and refractory to medical therapies. There are a handful of reports utilizing deep brain stimulation (DBS) to treat medically refractory PHM.
Case Report:
A 56-year-old woman developed PHM following an anoxic brain injury. Utilizing a stimulating and sensing DBS system, we show clinical improvement in myoclonus at 6 months and correlate it to local field potential (LFP) activity.
Discussion:
We present the first case to utilize DBS sensing to correlate LFP activity to myoclonus improvement. Our case contributes to the growing evidence of DBS for PHM.
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