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Budd-Chiari syndrome in a 33-year-old woman with hypercoagulable state: A case report

Laleh Abbasi1, Alireza Motamedi2, Ali Kiaee1

  • 1School of Medicine, Tonekabon branch, Islamic Azad University, Tonekabon, Iran.

Radiology Case Reports
|April 28, 2025
PubMed

Insights

Budd-Chiari syndrome (BCS), a rare hepatic venous outflow obstruction, was diagnosed in a woman with protein deficiencies. Early recognition and imaging are crucial for managing this complex condition.

Area of Science:

  • Hepatology
  • Vascular Medicine
  • Thrombosis Research

Background:

  • Budd-Chiari syndrome (BCS) results from hepatic venous outflow obstruction.
  • It is frequently associated with prothrombotic conditions.
  • Understanding these links is vital for patient management.

Observation:

  • A 33-year-old woman presented with abdominal pain and ascites.
  • Diagnosis of BCS was secondary to deficiencies in protein C, protein S, and antithrombin III.
  • Patient had a history of epilepsy, bipolar disorder, and poor medication adherence.

Findings:

  • Doppler ultrasound and contrast-enhanced CT confirmed BCS.
  • Treatment with anticoagulation and diuretics was initiated.
  • Recurrent ascites and behavioral issues complicated management, indicating a poor prognosis.

Implications:

  • This case underscores the importance of early BCS recognition.
  • Diagnostic imaging is critical for BCS confirmation.
  • Evaluating prothrombotic disorders in BCS patients can improve outcomes.

Keywords:
Budd-Chiari syndromeHepatic venous outflow obstructionHypercoagulable

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