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Enhanced near-infrared Ru (II) complex fluorescence sensor for sensitive sensing of Al3+ and cell imaging
Longlong Li1, Xiaolin Li1, Xinzhi Wang1
1University Featured Laboratory of Materials Engineering for Agricultural Machinery of Shandong Province, Intelligent Manufacturing College, Weifang University of Science and Technology, Shandong 262700, China.
Abstract:
A near-infrared (NIR) fluorescent sensor (λem = 790 nm), [Ru ((CH3O)2bipy)2 (BIMPY)]2+, was synthesized and thoroughly characterized, which can selectively recognize Al3+ ions in THF. The [Ru ((CH3O)2bipy)2 (BIMPY)]2+ has excellent sensitivity (LOD = 3.48 × 10-8 mol/L) towards Al3+ with a 2:1 (Ru complex/Al3+) complex ratio and opportune binding constant (K = 606.82 mol/L). The change mechanism of photophysical properties was determined by time-dependent density functional theory (TDDFT) method, which illustrates fluorescence enhancement sensing to Al3+ ions. The [Ru ((CH3O)2bipy)2 (BIMPY)]2+ was used as a field-deployable sensor, achieving on-site Al3+ monitoring via the RGB analysis. Furthermore, the [Ru ((CH3O)2bipy)2 (BIMPY)]2+ succeed in imaging Al3+ in living HepG2 cells.
