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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Determination of Efinaconazole in Plasma using Validated LC-MS/MS Technique

Govindarajan Srinivasan1,2, Asharani Indira Viswambaran1

  • 1Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632 014, Tamil Nadu, India.

Drug Metabolism and Bioanalysis Letters
|April 29, 2025
PubMed
Summary

A new LC-MS/MS method accurately quantifies efinaconazole in biological samples. This sensitive technique is crucial for pharmacokinetic and toxicology studies of the topical antifungal.

Keywords:
LC-MS/MSUS-FDA.efinaconazolefluconazolehuman plasmavalidation

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