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Subdermal Laser-Assisted Scar Subcision (SLASS) Combined With Fractional CO2 Laser for Acne Scars: Efficacy
Adrián Alegre-Sánchez1, Ana Suárez-Valle1, Diego Fernández-Nieto1
1Dermatology Clinic AB Derma, Madrid, Spain.
Journal of Cosmetic Dermatology
|April 29, 2025
Summary
Subdermal laser-assisted scar subcision (SLASS) effectively treats rolling acne scars by combining a 1470-nm diode laser with CO2 fractional laser. This innovative technique offers significant scar improvement with minimal adverse effects.
Area of Science:
- Dermatology
- Laser and light-based therapies
- Scar revision
Background:
- Rolling atrophic acne scars involve fibrous attachments to deeper skin layers.
- Traditional subcision is a common treatment for these scars.
Purpose of the Study:
- To evaluate the efficacy and safety of a novel technique: subdermal laser-assisted scar subcision (SLASS).
- SLASS combines a 1470-nm diode fiber laser with ablative fractional CO2 laser for rolling acne scars.
Main Methods:
- A retrospective study involving 42 patients treated with SLASS.
- Utilized a 1470-nm diode laser for subdermal scar release followed by fractional CO2 laser resurfacing.
- Specific laser parameters and energy settings were applied based on scar depth.
Main Results:
- Significant improvement in rolling acne scars observed, with mean reductions of 92.6 points on the ECCA scale and 1.67 points on the SCAR-S scale.
- Statistically significant differences (p < 0.05) were noted for both scales post-treatment.
- No severe adverse effects were reported among the patients.
Conclusions:
- Subdermal laser-assisted scar subcision (SLASS) is a promising treatment for rolling acne scars.
- The technique provides a thermo-mechanical effect, enhancing scar revision.
- Fractional CO2 laser in combination with laser-assisted subcision appears safe and effective.

