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Utilizing Physiologically Based Pharmacokinetic Models to Support Rational Medication in Chinese Elderly Population

Xiaofei Wu1, Ziyang Wang1, Shupeng Liu1

  • 1Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People's Republic of China.

Drug Design, Development and Therapy
|April 29, 2025
PubMed
Abstract

Keywords:
PBPK modelindividualized medicinepharmacokineticsrational medicationthe elderly

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