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Description of Hip Deformities in 5-Year-Old Patients with Congenital Zika Virus Syndrome: A Cross-Sectional Study
Herison Franklin Viana de Oliveira1, Francisco Robson Queiroz Rego2, Brauner de Souza Cavalcanti2
1Departamento de Cirurgia, Universidade Federal de Pernambuco, Recife, PE, Brasil.
Insights
Children with congenital Zika virus syndrome (CZS) often have hip luxation and severe functional limitations. While surgery improved hip abduction, radiographic changes were not significant, indicating a need for long-term studies.
Area of Science:
- Pediatrics
- Orthopedics
- Infectious Diseases
Background:
- Congenital Zika virus syndrome (CZS) can lead to significant musculoskeletal abnormalities.
- Hip alterations are a common concern in children diagnosed with CZS.
- Understanding these hip issues is crucial for managing long-term functional outcomes.
Purpose of the Study:
- To identify the most frequent hip alterations in children over five years old with CZS.
- To correlate clinical and radiographic findings with functional status.
- To evaluate the impact of surgical intervention on hip deformities.
Main Methods:
- Cross-sectional and retrospective study of 62 pediatric patients with CZS.
- Clinical data collected: hip abduction, contractures, and Gross Motor Function Classification System (GMFCS) levels.
- Radiographic data analyzed: Reimers index (RI), femoral neck-shaft angle (FNSA), and acetabular index (AI).
Main Results:
- Most patients (95.2%) presented with severe motor impairment (GMFCS IV and V).
- Elevated RI and AI were observed, particularly in patients with GMFCS V.
- Surgical tenotomy of hip adductor muscles improved abduction but showed no significant radiographic changes.
Conclusions:
- Children with CZS over five years old frequently exhibit hip luxation and severe functional deficits.
- Higher GMFCS levels correlate with increased hip luxation indicators (RI, AI).
- While surgical intervention aids mobility, long-term monitoring for hip deformities in CZS patients is essential.
Abstract:
Objective To report on the most prevalent hip alterations in children older than 5 with congenital Zika virus syndrome (CZS) per clinical and radiographic examinations. Methods Cross-sectional and retrospective study of 62 patients older than 5 with CZS. We extracted clinical data, including maximum abduction values, hip flexion contracture, gross motor function classification system (GMFCS) level, and radiographical data, including Reimers index (RI), femoral neck-shaft angle (FNSA), and acetabular index (AI), from medical records and radiographs and statistically evaluated them. Results The mean age of children was 65.6 ± 4.1 months. Most patients (95.2%) presented GMFCS scores of IV and V. Slow hip abduction was 41.2 ± 19.5°. The Thomas test revealed a mean deviation of 16.1 ± 14.9°. The mean values of RI, FNSA, and AI were 54.1 ± 34.1%, 158 ± 11.9°, and 26.0 ± 8.12°, respectively. Patients with GMFCS III and IV had lower RI and AI than those with a score of V. Regarding FNSA, there was no statistical difference between groups. Patients who underwent tenotomy of the hip adductor muscles presented greater abduction but no relevant radiographic differences. Conclusion There was a higher incidence of patients with hip luxation and more compromised functional degrees (GMFCS IV and V), and increased RI and AI in V. Operated patients presented abduction gain abduction but no radiographic improvement. Long-term studies are required to evaluate hip deformities in these subjects.
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