Description of Hip Deformities in 5-Year-Old Patients with Congenital Zika Virus Syndrome: A Cross-Sectional Study

Herison Franklin Viana de Oliveira1, Francisco Robson Queiroz Rego2, Brauner de Souza Cavalcanti2

  • 1Departamento de Cirurgia, Universidade Federal de Pernambuco, Recife, PE, Brasil.

PubMed

Insights

Children with congenital Zika virus syndrome (CZS) often have hip luxation and severe functional limitations. While surgery improved hip abduction, radiographic changes were not significant, indicating a need for long-term studies.

Area of Science:

  • Pediatrics
  • Orthopedics
  • Infectious Diseases

Background:

  • Congenital Zika virus syndrome (CZS) can lead to significant musculoskeletal abnormalities.
  • Hip alterations are a common concern in children diagnosed with CZS.
  • Understanding these hip issues is crucial for managing long-term functional outcomes.

Purpose of the Study:

  • To identify the most frequent hip alterations in children over five years old with CZS.
  • To correlate clinical and radiographic findings with functional status.
  • To evaluate the impact of surgical intervention on hip deformities.

Main Methods:

  • Cross-sectional and retrospective study of 62 pediatric patients with CZS.
  • Clinical data collected: hip abduction, contractures, and Gross Motor Function Classification System (GMFCS) levels.
  • Radiographic data analyzed: Reimers index (RI), femoral neck-shaft angle (FNSA), and acetabular index (AI).

Main Results:

  • Most patients (95.2%) presented with severe motor impairment (GMFCS IV and V).
  • Elevated RI and AI were observed, particularly in patients with GMFCS V.
  • Surgical tenotomy of hip adductor muscles improved abduction but showed no significant radiographic changes.

Conclusions:

  • Children with CZS over five years old frequently exhibit hip luxation and severe functional deficits.
  • Higher GMFCS levels correlate with increased hip luxation indicators (RI, AI).
  • While surgical intervention aids mobility, long-term monitoring for hip deformities in CZS patients is essential.