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Updated: May 9, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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The sigma-1 receptor: a mechanistically-informed therapeutic target for antidepressants

Naomi Xiao1,2, Liyang Yin1, Kayla M Teopiz1

  • 1Department of Research, Brain and Cognition Discovery Foundation, Toronto, Canada.

Expert Opinion on Therapeutic Targets
|April 29, 2025
PubMed
Abstract

Keywords:
Sigma-1 receptoranhedoniaantidepressantscognitiondextromethorphanglutamateketamine

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