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Published on: December 3, 2017
Alterations in coagulation profile of patients with periprosthetic joint infections
Augusto Carlos Maciel Saraiva1, Alan de Paula Mozella2,3, Hugo Alexandre de Araujo Barros Cobra2
1Orthopaedic Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Purpose:
This study aims to evaluate changes in the coagulation profile of patients with knee periprosthetic infections (PJI) and determine its diagnostic value in this complication.
Methods:
A prospective study was conducted with 112 patients who underwent revision surgery for total knee arthroplasty in a single tertiary hospital between January 2021 and December 2022.
Results:
51 patients were diagnosed with PJI. D-dimer (p = 0.001), fibrinogen (p = 0.0007), platelets (0.01), and international normalized ratio (p = 0.01) were significantly higher in patients with PJI.
Conclusions:
Patients with PJI display altered coagulation profile. The evaluation of coagulation-related markers has limited value for diagnosing PJI. Further studies are needed to understand the impact of such alterations on patients' outcomes.
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