[Attention deficit/hyperactivity disorder and cardiometabolic diseases: prevalence, etiology and treatment]

Sarah Kittel-Schneider1,2,3

  • 1Department of Psychiatry and Neurobehavioural Science, Acute Adult Mental Health Unit, Cork University Hospital, University College Cork, T12DC4A, Wilton, Cork, Irland. skittelschneider@ucc.ie.

Der Nervenarzt
|April 29, 2025
PubMed

Insights

Attention deficit/hyperactivity disorder (ADHD) is closely linked to cardiometabolic diseases throughout life. Management requires personalized treatment addressing lifestyle, therapy, and medication side effects.

Area of Science:

  • Neuroscience
  • Cardiology
  • Endocrinology

Background:

  • Attention deficit/hyperactivity disorder (ADHD) is associated with an elevated risk of cardiometabolic diseases across the lifespan.
  • These conditions include obesity, diabetes mellitus, and arterial hypertension.
  • Underlying causes involve genetic, dopaminergic, circadian, and inflammatory factors, alongside lifestyle influences.

Purpose of the Study:

  • To explore the connection between ADHD and cardiometabolic diseases.
  • To outline the multifactorial causes contributing to this comorbidity.
  • To discuss treatment strategies for individuals with ADHD and co-occurring cardiometabolic conditions.

Main Methods:

  • Literature review of existing research on ADHD and cardiometabolic health.
  • Analysis of etiological factors linking ADHD to metabolic and cardiovascular issues.
  • Examination of current therapeutic approaches and their considerations.

Main Results:

  • A significant correlation exists between ADHD and increased incidence of obesity, diabetes, and hypertension.
  • Multiple factors contribute to this comorbidity, including genetics, dopamine pathways, and lifestyle.
  • Treatment necessitates a comprehensive, individualized plan.

Conclusions:

  • The link between ADHD and cardiometabolic diseases is well-established and spans the entire lifespan.
  • Effective management involves addressing underlying causes and tailoring interventions.
  • Pharmacotherapy for ADHD must carefully consider potential cardiometabolic side effects.

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