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Plausible Deniable Medical Image Encryption by Large Language Models and Reversible Content-Aware Strategy
IEEE Journal of Biomedical and Health Informatics
|April 29, 2025
Summary
This study introduces a novel medical image encryption method using Large Language Models (LLMs) to enhance DNA encoding. The LLM-enhanced DNA encoding offers superior security and efficiency for protecting sensitive patient data.
Area of Science:
- Computer Science
- Medical Imaging
- Cryptography
Background:
- Healthcare systems face significant security risks, with data loss potentially causing severe harm to patients and institutions.
- DNA encoding presents a promising solution for medical image encryption due to its speed, parallelism, minimal storage, and robust security.
Purpose of the Study:
- To propose an advanced medical image encryption technique by integrating Large Language Models (LLMs) with DNA encoding.
- To enhance the security and efficiency of medical image data protection against privacy breaches.
Main Methods:
- The proposed method features an LLM enhancing module to compress low-entropy medical image pixels into compact, probabilistic signals, adding a layer of defense.
- A content-aware permutation and diffusion module further secures data by breaking pixel correlations and increasing cryptographic complexity via DNA-based diffusion.
Main Results:
- Experiments on ChestXray-14, COVID-CT, and fcon-1000 datasets demonstrated superior performance compared to existing methods.
- The LLM-enhanced DNA encoding method showed significant improvements in sensitivity, correlation, and entropy metrics.
Conclusions:
- The LLM-enhanced DNA encoding method provides a highly effective and secure approach for medical image encryption.
- This technique offers a robust solution for safeguarding sensitive medical data in healthcare systems.
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