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Long-term Trends In The Burden Of Migraine In China: A Comprehensive Analysis From 1990 To 2021 And Projections To 2035.

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Long-term Trends In The Burden Of Migraine In China: A Comprehensive Analysis From 1990 To 2021 And Projections To 2035.

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Long-Term Trends in the Burden of Migraine in China: A Comprehensive Analysis from 1990 to 2021 and Projections to

Cifeng Zhang¹, Xiaoping Wang²

¹Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, China.

Neuroepidemiology

|April 29, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Migraine significantly impacts China, affecting millions annually, especially women. Projections indicate a continued rise in cases through 2035, necessitating targeted public health interventions.

Keywords:

Age-period-cohort analysis Bayesian age-period-cohort Global burden of disease Joinpoint regression Migraine

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Area of Science:

Neurology
Public Health
Epidemiology

Background:

Migraine is a prevalent neurological disorder with a significant impact on quality of life.
Limited data exists on the specific burden of migraine within China.
This study addresses the data gap by analyzing long-term trends and future projections.

Purpose of the Study:

To analyze long-term trends in migraine incidence, prevalence, and DALYs in China from 1990 to 2021.
To identify key demographic and lifestyle factors influencing migraine burden.
To project future migraine trends in China up to 2035.

Main Methods:

Utilized the Global Burden of Disease (GBD) 2021 database for comprehensive data.
Employed joinpoint regression for temporal trend analysis.

Applied age-period-cohort (APC) analysis and Bayesian modeling for influence identification and future projections.

Main Results:

Substantial burden: 13.04 million new cases annually, 184.75 million prevalent cases, and 6.98 million DALYs.
Females disproportionately affected, with peak prevalence in the 30-49 age group.
Increased susceptibility observed in individuals born post-1960, linked to demographic and lifestyle shifts; population growth drives prevalence increases.

Conclusions:

Migraine represents a significant and growing public health challenge in China.
Women are particularly vulnerable, requiring focused attention.
Urgent need for targeted prevention, early detection, and intervention strategies to manage the escalating burden.