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Related Experiment Video

Updated: Jul 5, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

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Published on: February 26, 2013

Association between surrogate insulin resistance markers and postablation atrial fibrillation recurrence: A

Hamed Ghoshouni¹, Alireza Sepehri Shamloo², Seyed Reza Mirjalili³

¹Cardiovascular Epidemiology Research Center, Rajaie Cardiovascular Institute, Tehran, Iran; Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.

|April 29, 2025

Summary

Insulin resistance markers like the triglyceride-glucose index predict atrial fibrillation recurrence after ablation. These markers can help identify patients at higher risk, guiding preventive strategies for better outcomes.

Keywords:

Ablation Arrhythmia Atrial fibrillation Diabetes Insulin resistance

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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

Area of Science:

Cardiology
Metabolic Syndrome
Electrophysiology

Background:

Atrial fibrillation (AF) is a common arrhythmia with high recurrence rates post-ablation.
Insulin resistance is increasingly recognized as a factor influencing cardiovascular health.
Previous research suggests a link between insulin resistance markers and AF recurrence.

Purpose of the Study:

To systematically review and meta-analyze studies on surrogate insulin resistance markers and AF recurrence after ablation.
To assess the predictive value of various insulin resistance markers for post-ablation AF recurrence.

Main Methods:

Systematic review and meta-analysis of observational studies.
Searched PubMed, Web of Science, Embase, and Scopus up to August 2024.
Included 9 studies with 7729 participants; used random-effects model and Newcastle-Ottawa scale for bias assessment.

Main Results:

Triglyceride-glucose index (HR 1.29), HOMA-IR (HR 1.27), and MIRSI (HR 1.04) were significantly associated with AF recurrence.
Triglyceride-to-HDL ratio showed no significant association (HR 1.09).
Low heterogeneity observed for HOMA-IR and MIRSI.

Conclusions:

Surrogate markers of insulin resistance are valuable predictors of AF recurrence post-ablation.
These markers may aid in identifying patients for targeted preventive strategies.
Further prospective studies are needed to confirm these findings and their clinical utility.