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Multimodality Management of Skin Hyperpigmentation
Amer Salman Almansory1, Zainab Salem Alhamdany2
1College of Medicine, University of Basrah, Basra, Iraq. amer_dd@yahoo.com.
Aesthetic Plastic Surgery
|April 29, 2025
Summary
Combining Q-switched Nd:YAG laser with medical therapy significantly improves skin hyperpigmentation. This multimodal approach enhances patient satisfaction and clinical outcomes over successive treatment sessions.
Area of Science:
- Dermatology
- Aesthetic Medicine
Background:
- Skin hyperpigmentation, driven by excess melanin, causes aesthetic and psychological distress.
- Q-switched Nd:YAG laser is a primary treatment, with efficacy varying by skin type, fluence, and frequency.
- Multimodal treatments combining laser and medical therapies may offer improved results.
Purpose of the Study:
- To evaluate the efficacy and safety of Q-switched Nd:YAG laser combined with medical therapy for hyperpigmentation.
- To assess clinical outcomes and patient satisfaction.
- To analyze the influence of demographic and lifestyle factors on treatment response.
Main Methods:
- A randomized cross-sectional study involved 300 patients treated between January 2022 and September 2023.
- Treatment response was evaluated via clinical assessments and Likert scale patient satisfaction.
- Factors including gender, sun exposure, pregnancy, and hormonal influences were analyzed.
Main Results:
- A high percentage of participants were female (92.6%).
- Significant improvements in clinical evaluation and patient satisfaction were observed across treatment sessions.
- Patient satisfaction rated "Good" increased from 80.6% to 98.3%; male patients showed a stronger response than females.
- No significant impact of analyzed factors (gender, sun exposure, pregnancy, hormonal influences) on outcomes was found.
Conclusions:
- Comprehensive hyperpigmentation assessment is vital for selecting optimal treatments.
- A multimodal strategy integrating Q-switched Nd:YAG laser and medical therapy surpasses single-modality treatments.
- Treatment outcomes demonstrate progressive improvement with each session.
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