Related Experiment Video

Updated: May 9, 2025

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.2K

Impact of Mental Health Disorders in Patients with Myocardial Infarction with Non-obstructive Coronary Arteries: A

Abdul Rasheed Bahar1, Paawanjot Kaur1, Yasemin Bahar1

  • 1Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA.

Journal of General Internal Medicine
|April 29, 2025
PubMed

Insights

Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and mental health disorders face higher mortality and adverse outcomes. Integrated care is crucial for improving prognosis in these high-risk MINOCA patients.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Myocardial infarction with non-obstructive coronary arteries (MINOCA) lacks clear causes and defined outcomes.
  • The impact of mental health disorders on MINOCA patient prognosis is understudied.
  • Cardiovascular risk is linked to mental health conditions, necessitating further investigation.

Purpose of the Study:

  • To investigate the association between mental health disorders and in-hospital outcomes in MINOCA patients.
  • To determine if mental health conditions independently affect mortality and adverse events in MINOCA.

Main Methods:

  • Retrospective cohort study using the National Inpatient Sample (NIS) from 2017-2021.
  • Identified MINOCA patients with and without mental health disorders using ICD-10-CM codes.
  • Employed propensity score matching and inverse probability weighting (IPW) for confounder adjustment.

Main Results:

  • MINOCA patients with mental health disorders exhibited higher in-hospital mortality (2.26% vs 1.21%).
  • Increased risks of sudden cardiac arrest (1.51% vs 0.65%), pulmonary embolism (1.54% vs 0.65%), and acute kidney injury (25.45% vs 20.24%) were observed.
  • These outcomes remained significant after propensity score matching.

Conclusions:

  • Mental health disorders are independently linked to worse in-hospital outcomes in MINOCA patients.
  • Findings underscore the need for integrated cardiovascular and psychiatric care.
  • Early screening and multidisciplinary management are vital for improving MINOCA patient outcomes.
Abstract

Keywords:
In-hospital mortalityMental health disordersMyocardial infarctionNon-obstructive coronary artery disease

More Related Videos

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

3.2K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.3K

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
14
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.1K
Imbalances in Cardiac Output01:23

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to...
1.2K
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
47
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
1.8K
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
479