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Histone tetrasome dynamics affects chromatin transcription.

Xiangyan Shi1, Anastasiia S Fedulova2, Elena Y Kotova3

  • 1Department of Biology, Shenzhen MSU-BIT University, No. 1, International University Park Road, Longgang District, Shenzhen, Guangdong Province 518172, China.

Nucleic Acids Research
|April 30, 2025
PubMed
Summary

Subnucleosomes called tetrasomes, lacking histone dimers, exhibit increased mobility and reduced DNA interactions. This dynamic structure presents a lower barrier for RNA polymerase II, impacting nuclear processes.

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