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Multipotency and Niche of Bulge Stem Cell

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

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Related Experiment Video

Updated: May 9, 2025

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

Patchy Alopecia in a Male Patient Following Temple Filler Injection

Hudson Dutra Rezende¹, Fernanda Bighetti Facó¹, Maria Fernanda Reis Gavazzoni Dias²

¹Fundação Lusíada, UNILUS, Santos, São Paulo, Brazil.

International Journal of Dermatology

|April 30, 2025

Summary

No abstract available in PubMed .

Keywords:

aesthetic complications alopecia hyaluronic acid fillers

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