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Time-Restricted Eating is a Feasible Dietary Strategy in the Treatment of Complicated Type 2 Diabetes: The RESET2
Anne-Ditte Termannsen1, Annemarie Varming2, Gitte S Hansen2
1Steno Diabetes Center Copenhagen, Copenhagen University Hospital, Herlev, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Objective:
To investigate the feasibility of a 12-week time-restricted eating (TRE) intervention targeting people with overweight/obesity and complicated type 2 diabetes to inform the design of a 1-year randomized controlled trial.
Methods:
In this single-arm pilot study, 20 participants with overweight/obesity and complicated type 2 diabetes were recruited from the diabetes clinics at Hvidovre Hospital and Steno Diabetes Center Copenhagen in the Greater Copenhagen area, Denmark. Participants followed 8 weeks of strict 10-hour TRE, followed by a 4-week TRE period with individual adjustments and support options.
Results:
Nineteen participants completed the intervention. Median (quartile 1-quartile 3) adherence to the eating window across all 12 weeks was 94% (86-98). Mean (95% confidence interval) reductions in body weight of -2.0 kg (-2.9 to -1.1) and hemoglobin A1c of -0.4% (-0.6 to -0.1) were observed. Participants expressed that the individualized options added flexibility to the eating concept, enabled the maintenance of social life, and eased challenging times with TRE.
Conclusions And Implications:
Twelve weeks of TRE was feasible. Individualized adjustments and support may have the potential to facilitate the maintenance of long-term TRE.
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