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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
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Explainable CNN for brain tumor detection and classification through XAI based key features identification.

Shagufta Iftikhar1, Nadeem Anjum1, Abdul Basit Siddiqui1

  • 1Department of Computer Science, Capital University of Science and Technology, Islamabad, Pakistan.

Brain Informatics
|April 30, 2025
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Summary

This study introduces a simpler, interpretable brain tumor classification model using Explainable AI (XAI) and Convolutional Neural Networks (CNNs). The novel approach achieves high accuracy, focusing on relevant features for reliable tumor detection and classification.

Keywords:
Brain tumor classificationConvolutional neural networkDeep learningExplainable AI

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computational Neuroscience

Background:

  • Existing brain tumor classification models often exhibit complex structures, hindering interpretability and potentially leading to reliance on irrelevant features.
  • Model complexity increases the number of layers and parameters, complicating the classification process and reducing transparency.

Purpose of the Study:

  • To develop a novel methodology combining Explainable AI (XAI) techniques with a simplified Convolutional Neural Network (CNN) architecture for brain tumor classification.
  • To enhance model transparency and robustness by ensuring focus on relevant features and reducing complexity.

Main Methods:

  • Integration of XAI techniques, including Gradient-weighted Class Activation Mapping (Grad-Cam), Shapley Additive explanations (Shap), and Local Interpretable Model-agnostic Explanations (LIME), with a CNN architecture.
  • Minimization of network layers to reduce model complexity and improve focus on critical features for tumor detection.

Main Results:

  • The proposed model achieved 99% accuracy on seen data and 95% accuracy on unseen data, demonstrating strong generalizability and reliability.
  • XAI techniques provided clear insights into the model's decision-making process, confirming focus on relevant tumor features.

Conclusions:

  • The developed approach offers a balance of simplicity, interpretability, and high accuracy in brain tumor classification.
  • This methodology represents a significant advancement, improving transparency and reliability in medical image analysis for brain tumor detection.