Primary Typical Carcinoid Tumor of the Sphenoid Sinus: Case Report and Literature Review

Carcinoid tumors, a subset of neuroendocrine tumors, are exceptionally rare in the nose and paranasal sinuses. Owing to their indolent nature, nonspecific clinical symptoms, and variable radiological features, treatment of carcinoid tumors remains a challenge. In this report, we present a case involving a 49 year-old female patient who presented with a carcinoid tumor originating in the sphenoid sinuses. The patient underwent a surgical resection of the tumor and has been followed up in the outpatient clinic, recurrence-free. In addition, we performed an English literature search of cases of carcinoid tumor of the nose and paranasal sinuses from January 2000 through January 2024 in the MEDLINE, EMBASE, and Scopus databases. Furthermore, the clinical characteristics and interventions of carcinoid tumor of the nose and paranasal sinuses were discussed, which might enhance the early diagnosis and provide appropriate management strategies.