Unusual skull metastasis in colorectal adenocarcinoma

Colorectal cancer ranks as the third most commonly diagnosed cancer globally. Research suggests that colon cancer and rectal cancer differ in terms of aetiology and risk factors. Follow-up is essential due to the detrimental impact of metastasis on patient survival (5-year survival rate of less than 20%). Routine use of positron emission tomography (PET-CT) is not recommended. This case report describes an elderly woman diagnosed who had previously been treated for rectal cancer. CT scans of the abdomen and chest showed no evidence of metastatic disease. During the second year of follow-up, a PET-CT was performed and a new active osseous lesion in the skull was identified. Current follow-up guidelines for colorectal carcinoma may not encompass all potential metastatic sites. Incorporating full body PET-CT scans into the follow-up protocol could be beneficial for detecting additional metastatic sites.