Transcatheter tricuspid valve replacement: will it prevail?

Area of Science:

• Cardiology
• Interventional Cardiology
• Cardiac Surgery

Background:

• Severe tricuspid regurgitation (TR) presents significant morbidity and mortality, with limited success from medical therapy alone.
• Conventional surgery for TR carries high mortality, especially as a standalone procedure.
• Transcatheter tricuspid interventions offer new options, but limitations exist for repair procedures.

Purpose of the Study:

• To review the latest advancements in transcatheter tricuspid valve replacement (TTVR) devices and clinical findings.
• To discuss the challenges, limitations, patient selection, and outcomes of TTVR for severe TR.
• To highlight the transformative potential of TTVR in managing severe TR.

Main Methods:

• Review of current literature on transcatheter tricuspid valve replacement (TTVR) technologies and clinical studies.
• Analysis of patient selection criteria, procedural techniques, and reported outcomes for TTVR.
• Discussion of the evolving landscape and future directions in TTVR for severe tricuspid regurgitation.

Main Results:

• Transcatheter tricuspid valve replacement (TTVR) is emerging as a viable alternative for patients with severe TR, particularly those at high surgical risk.
• Recent advancements in TTVR devices demonstrate potential for effective treatment, though challenges remain.
• Clinical findings indicate TTVR offers a promising therapeutic avenue, expanding treatment options beyond repair.

Conclusions:

• Transcatheter tricuspid valve replacement (TTVR) represents a significant advancement in managing severe tricuspid regurgitation (TR), especially for high-risk populations.
• Careful patient selection and ongoing technological development are crucial for optimizing TTVR outcomes.
• TTVR holds considerable promise to reshape the treatment paradigm for severe TR, improving patient survival and quality of life.