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Updated: May 9, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Anatomic Multiple Ligament Reconstructions of the Knee.
Edward R Floyd1,2, Gregory B Carlson3, Jill K Monson4
1Twin Cities Orthopedics, Minneapolis, Minnesota, USA.
This study details a single-stage surgical technique for complex knee ligament injuries, emphasizing anatomic reconstruction and early motion for optimal outcomes in multiple cruciate and posterolateral corner ruptures.
Area of Science:
- Orthopedic Surgery
- Sports Medicine
- Knee Reconstruction
Background:
- Multiple ligament knee injuries often result from athletic activities.
- These injuries can involve cruciate ligaments, collateral ligaments, and associated damage to meniscus, bone, cartilage, and nerves.
Purpose of the Study:
- To describe a surgical technique for managing combined anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), and posterolateral corner (PLC) ruptures.
- To highlight the importance of anatomic reconstruction and early rehabilitation in achieving successful outcomes.
Main Methods:
- Surgical technique involves neurolysis of the common peroneal nerve (CPN), tendon repairs, and anatomic-based ligament reconstructions.
- Utilized autografts and allografts for ACL, PCL, and PLC reconstruction with precise tunnel placement and graft tensioning sequence.
- Emphasized 3D modeling for optimal tunnel orientation and established graft tensioning order (PCL, ACL, PLC).
Main Results:
- Anatomic single-stage reconstruction has shown successful outcomes for various multiligament knee injuries.
- Equivalent results reported for acute versus chronic injuries and different injury patterns when anatomic principles are followed.
- Early range of motion and specific bracing protocols are crucial for preventing complications.
Conclusions:
- Single-stage anatomic reconstruction is the gold standard for complex knee ligament injuries.
- Early knee range of motion (0°-90°) and PCL-bracing are vital post-operatively to prevent arthrofibrosis and graft stretching.
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