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Updated: May 12, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Gold-Catalyzed Deallylative C-S Cross-Coupling Reactions

Prafulla Bera1, Tanmayee Nanda1, Nayan A Barhate1

  • 1Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri 462 066, India.

Organic Letters
|May 1, 2025
PubMed
Summary

This study introduces a novel gold-catalyzed deallylative C-S cross-coupling using a ligand-enabled Au(I)/Au(III) redox cycle. Allyl phenyl sulfide acts as a sulfur surrogate, preventing catalyst deactivation and enabling efficient coupling reactions.

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