Nurse-Administered Sedation in Digestive Endoscopy: A Systematic Review
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Updated: May 9, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Miriam Hidalgo-Cabanillas1,2, José Alberto Laredo-Aguilera2,3,4, Esperanza Barroso-Corroto2,3,4
1Hospital Universitario de Toledo, 45004 Toledo, Spain.
Abstract:
Background/Objectives: Nurses are becoming increasingly common healthcare professionals who perform sedation in digestive endoscopy services. Efficacy, safety and patient satisfaction are indicators of quality and safety in the administration of sedation by nurses in patients undergoing digestive endoscopy. Therefore, the aim of this study was to synthesize the scientific evidence available to date on the efficacy, safety and patient satisfaction of nurse-administered sedation during digestive endoscopies. Methods: A systematic review was conducted according to PRISMA standards. The PubMed, Scopus, SciELO, Web of Science and LILACS databases were consulted. Narrative synthesis and descriptive statistics were used to explore complications arising from the use of sedation by nurses, using the percentage of complications and total events in the included studies. Owing to the methodology and heterogeneity of the included studies, a meta-analysis was not possible. Results: A total of 292 studies were collected, 13 of which were selected. In terms of efficacy, studies indicate that nurse sedation is effective in ensuring patient comfort and optimizing procedure times. On the other hand, studies have evaluated the safety of sedation, measured complications during sedation and reported incident and minor complication rates of less than 2.5%. Finally, studies analyzing patient satisfaction and patient experience have demonstrated high levels of satisfaction. Conclusions: Nurse-administered sedation demonstrates high efficacy in ensuring patient comfort and optimizing procedure times. Nurse-administered propofol sedation is safe for endoscopic procedures, with low rates of significant adverse events. Patients reported high levels of satisfaction with nurse-administered sedation, with reduced discomfort and improved perceptions of the quality of the procedure.
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